Don't think that you’re ever too good to respond to a fan.
Number 1 rule of social media: you’re not Kanye.
Only following your well-endowed wife on Twitter won’t cut it. In the beginning, every follower counts. If someone is willing to take out time from their busy schedule to respond to your inane ramblings, you’d better hit them back with the quickness.
Fans willing to follow you before the fame are the ones you want to cultivate. Chances are half of them will say you changed once that first Pitchfork review comes in, but the remaining few will always represent your core. No matter how potentially famous you think you’ll be one day, you're still starting at the ground floor in the beginning. Taking time to respond to your early supporters is what helps you gain traction later down the line.